Searchable abstracts of presentations at key conferences in endocrinology

ea0014p215 | (1) | ECE2007

Absence of TSH-induced increase in leptin levels in patients with history of differentiated thyroid carcinoma undergoing rhTSH testing

Cecoli Francesca , Andraghetti Gabriella , Ghiara Carla , Briatore Lucia , Cavallero Domenico , Mussap Michele , Minuto Francesco , Giusti Massimo

Some extra-thyroid effects of TSH have been described in vitro and in vivo. TSH has recently been suggested to induce IL-6 secretion from adipocytes. Leptin is the main secretory protein from adipose tissue. Our aim was to evaluate the acute effect of rhTSH-induced TSH surge on serum leptin levels in differentiated thyroid carcinoma (DTC) patients. Ten patients (2 m, 8 f; age range 31–66 years) with stage 1-3 DTC were evaluated during scheduled standard rhTS...